Codon Usage in Hemoglobin Coding Genes

hemoglobin, codon usage, codon preference..

Authors

  • Li Gun Department of Biomedical Engineering, School of Electronics and Information Engineering, Xi'an Technological University, Xi'an, Shaanxi Province, China
  • Tian Han Department of Biomedical Engineering, School of Electronics and Information Engineering, Xi'an Technological University, Xi'an, Shaanxi Province, China
  • Ren Yumiao Department of Biomedical Engineering, School of Electronics and Information Engineering, Xi'an Technological University, Xi'an, Shaanxi Province, China
  • Du Ning Department of Biomedical Engineering, School of Electronics and Information Engineering, Xi'an Technological University, Xi'an, Shaanxi Province, China
September 14, 2017

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Hemoglobin is a protein responsible for the transport of oxygen. The preference of hemoglobin coding gene is analyzed by CodonW. The relationship between the A3 / (A3 + T3) and G3 / (G3 + C3) and the relationship between GC12 and GC3 are all investigated. Finally, the preference of hemoglobin coding gene is shown and discussed. The results show that codon use preference of CUG, CGU, UAA, ACC, GUG and GGC are greater than 2.5. This information facilitates an improved understanding of the structural, functional of hemoglobin